C. diff Vaccine

A new vaccine study designed to help protect against C. diff, sometimes referred to as the “hospital bug.”

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Trial Overview

We are currently recruiting for a new vaccine study designed to help protect against Clostridioides difficile (C. diff), sometimes referred to as the “hospital bug.”

You will receive 2 doses of the investigational C. diff vaccine or placebo (injection with no vaccine). Participation lasts for up to 3 and a half years and includes at least 8 study visits.

Participation Criteria

  • Aged 65 and over
  • At an increased risk of a C. Diff infection. Risk factors can include recent antibiotic use, a hospital stay or emergency room visits within the past year, frequent outpatient appointments, or a planned hospital admission or elective surgery

What is Clostridioides difficile (C. diff)?

C. diff (Clostridioides difficile) is a bacterium that can infect the large intestine, causing symptoms ranging from mild diarrhoea to severe, life-threatening inflammation of the colon (colitis). It most commonly affects people who have recently taken antibiotics, which disrupt the normal gut bacteria and allow C. diff to grow out of control and produce toxins that damage the intestinal lining. It spreads via spores that are resistant to many disinfectants, making it highly contagious in healthcare settings like hospitals and care homes.

Find out more: 

Complete the enquiry form and a member of staff will be in contact to discuss further.

Call us on 028 9027 8380 to discuss with the team.